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International Journal of Poultry Science

.: Home > International Journal of Poultry Science > 2009 > Volume 8 Number 1 > M.S. Islam1, M.A. Awal1, M. Mostofa1, F. Begum1, A. Khair1 and M. Myenuddin2

Effect of Spirulina on Biochemical Parameters and Reduction of Tissue Arsenic Concentration in Arsenic Induced Toxicities in Ducks

M.S. Islam1, M.A. Awal1, M. Mostofa1, F. Begum1, A. Khair1 and M. Myenuddin2
1Department of Pharmacology, 2Department of Physiology, Bangladesh Agricultural University, Mymensingh - 2202, Bangladesh
Abstract :

The present study was undertaken for the effect of spirulina on biochemical parameters and
reduction of tissue arsenic concentration in arsenic induced toxicities in ducks. One hundred and seventy
5 ducklings were divided into five equal groups separately. One group (T ) of ducklings was kept as control. 0 One group (T ) of ducklings were given arsenic trioxide @ 100 mg/L drinking water and rest three groups of 1 ducklings (T , T and T ) were given arsenic trioxide @ 100 mg/L plus spirulina in three different doses i.e. 2 3 4 30, 60 and 120 mg/L in drinking water daily for 90 days starting from day 15. Five birds were sacrificed from each group in every 15 day intervals and biochemical parameters were determined. All the biochemical parameters (SGPT, SGOT, ALP, LDH and ACP) were significantly (p<0.01) elevated in arsenic treated groups. However, the elevation of these parameters was less in arsenic plus spirulina treated groups (T , T and T ). 2 3 4 The distribution of arsenic concentration was highest in liver and lowest in faeces. Maximum reduction of arsenic was recorded in all organs following highest doses of spirulina (120 mg/L). The present study reveals that spirulina may be helpful for reducing the tissue burden of arsenic in ducks.

Keywords :
Spirulina, biochemical parameters, arsenic tissue concentration, arsenic toxicities, ducks

Date Deposited : 05 Jul 2011 10:05

Last Modified : 05 Jul 2011 10:05

Official URL: http://www.pjbs.org/ijps/ijps.htm

Volume 8, Number 1, - 2009 , ISSN 1682-8356

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