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International Journal of Poultry Science

.: Home > International Journal of Poultry Science > 2009 > Volume 8 Number 2 > B. Baurhoo1, F. Goldflus2 and X. Zhao1

Purified Cell Wall of Saccharomyces cerevisiae Increases Protection Against Intestinal Pathogens in Broiler Chickens

B. Baurhoo1, F. Goldflus2 and X. Zhao1
1Department of Animal Science, McGill University, Ste. Anne de Bellevue, H9X 3V9, QC, Canada 2Biorigin, Sمo Paulo, SP, Brazil
Abstract :

A study was conducted to determine effects of a mannanoligosaccharide prebiotic, derived from
cell wall of the yeast Saccharomyces cerevisiae, on morphological development of the intestines and
microbial populations of the ceca and litter. Dietary treatments included: antibiotic-free diet (CTL), diet 1 +
virginiamycin (VIRG; 16.5 mg/kg feed) and diet 1 + ActiveMOS (MOS; 1.5 kg/T starter diet and 1 kg/T grower
diet). Each treatment was assigned to 3 pen replicates (55 birds/pen). At day 14, 24 and 34, cecal contents
were used for Lactobacilli, Bifidobacteria, E. coli and Campylobacter quantification whereas litter was
analyzed for Campylobacter and E. coli. At same time points, jejunum samples were used in histological
analysis. MOS significantly increased goblet cell number in the jejunum (p<0.05) at day 24 and 34. In contrast to the CTL and VIRG diet, MOS consistently increased cecal populations of Bifidobacteria (p<0.05) at all times. Moreover, at day 34, MOS increased cecal populations of Lactobacilli (p<0.05) and reduced E. coli and Campylobacter concentrations (p<0.05). None of the dietary treatments altered E. coli and Campylobacter concentrations in the litter. In comparison to antibiotics, MOS, therefore, improved intestinal health conditions by increasing goblet cell number into the villi membrane, stimulating growth of beneficial bacteria and reducing colonization by pathogenic bacteria.

Keywords :
Antibiotic, mannanoligosaccharides, bacteria, goblet cells, broil

Date Deposited : 05 Jul 2011 10:43

Last Modified : 05 Jul 2011 10:43

Official URL:

Volume 8, Number 2, - 2009 , ISSN 1682-8356

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