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International Journal of Poultry Science

.: Home > International Journal of Poultry Science > 2009 > Volume 8 Number 5 > G.T. Pharr1, A.M. Cooksey1, B.M. McGruder2, B. Felfoldi1, E.D. Peebles2, M.T. Kidd2 and J.P. Thaxton2

Ephrin Receptor Expression in the Embryonic Bursa of Fabricius

G.T. Pharr1, A.M. Cooksey1, B.M. McGruder2, B. Felfoldi1, E.D. Peebles2, M.T. Kidd2 and J.P. Thaxton2
1Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, USA 2Department of Poultry Science, Mississippi State University, Mississippi State, MS 39762, USA
Abstract :

Utilizing degenerate PCR primers complementary to conserved regions within the kinase domain
of Receptor Tyrosine Kinase (RTK) genes, the goal was to compare the full complement of RTK expressed
(mRNA level) between two developmental stages of bursal B-cells. We identified 21 different RTK cDNAs
out of a total of 235 cDNAs sequenced between the two B-cell stages. The dataset revealed the expression
of RTK genes important in developmental processes, namely the ephrin receptors (Eph). The ephrin
receptors and the ephrin ligands play critical roles in embryo development by controlling the organization of
cells in tissues and by inducing cellular differentiation.

Keywords :
Bursa of fabricius, B-cell, receptor tyrosine kinase, ephrin receptor

Date Deposited : 05 Jul 2011 13:04

Last Modified : 05 Jul 2011 13:04

Official URL: http://www.pjbs.org/ijps/ijps.htm

Volume 8, Number 5, - 2009 , ISSN 1682-8356

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