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International Journal of Poultry Science

.: Home > International Journal of Poultry Science > 2007 > Volume 6 Number 3 > Shaban Rahimi1, Ehsan Salehifar1, Seyed Ali Ghorashi2, Jesse L. Grimes3 and Mohammad A. Kaimi Torshizi1

The Effect of Egg-Derived Antibody on Prevention of Avian Influenza Subtype H N in Layer Chicken

Shaban Rahimi1, Ehsan Salehifar1, Seyed Ali Ghorashi2, Jesse L. Grimes3 and Mohammad A. Kaimi Torshizi1
1Department of Poultry Science, Tarbiat Modares University, Tehran, Iran 2National Research Center for Genetic Engineering and Biotechnology of Iran, Tehran, Iran 3Department of Poultry Science, North Carolina State University, Raleigh NC, USA
Abstract :

Avian Influenza (AI) is a contagious disease of poultry which caused by type A influenza virus. In the present outbreak of AI in Iran, the isolates (H N ) were characterized as a low pathogenic form of the 9 2 virus. Outbreaks due to H N subtypes have been reported in many countries. Because the common 9 2 methods of control of outbreaks of AI may not be very effective to prevent and control of this disease, we decided to study the effect of egg derived antibody on reducing morbidity and spread of virus in a population of chickens by using so-called transmission experiments. Birds in test group (which received antibody in
drinking water) had lower morbidity (p<0.05) and virus shedding compared to the control group. Our experiments demonstrate that administration of egg derived antibody (Ab) to chickens, not only may protect
birds against this disease but is also an effective strategy to reduce transmission of AI virus. Therefore,  egg derived specific antibody can be an attractive tool to prevent outbreaks of AI viruses in poultry, thereby
achieving the aim of eliminating the source of human infections.

Keywords :
Avian influenza, antibody, egg, layer chicken

Date Deposited : 14 Jul 2011 12:55

Last Modified : 14 Jul 2011 12:55

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Volume 6, Number 3, - 2007 , ISSN 1682-8356

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