UMM Logo

Universitas Muhammadiyah Malang


Free Download Journals Directory


International Journal of Medical Sciences

.: Home > International Journal of Medical Sciences > 2007 > Volume 4 Number 5 > Keisuke Nakano1, 2, Takehiro Watanabe1, Takako Shimizu2, and Toshiyuki Kawakami 1, 2

Immunohistochemical Characteristics of Bone Forming Cells in Pleomorphic Adenoma

Keisuke Nakano1, 2, Takehiro Watanabe1, Takako Shimizu2, and Toshiyuki Kawakami 1, 2
1. Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine, Shiojiri, Japan 2. Hard Tissue Pathology Unit, Matsumoto Dental University Institute for Oral Science, Shiojiri, Japan
Abstract :

Histopathological and immunohistochemical examinations were carried out in a case of  leomorphic adenoma with bone formation, occurring in the chin of a 34-year-old Japanese man. Examination results showed the modified neoplastic myoepithelial cells reacted positively to S-100 protein. The S-100-positive modified neoplastic myoepithelial cells were proliferated in the closely related area of the bone tissue. Furthermore, positive reaction was detected in the bone forming cells: osteoblasts and osteocytes. These cells also reacted positively to Runx2 as a marker of bone forming cells. These results suggest that the origin of the bone forming  cells in this case of pleomorphic adenoma was modified neoplastic myoepithelial cells.

Keywords :
Bone forming cells, Immunohistochemical characteristics, Pleomorphic adenoma, Modified myoepithelial cell, Trans-differentiation

Date Deposited : 29 Jul 2011 10:44

Last Modified : 29 Jul 2011 10:44

Official URL: http://www.medsci.org/archive

Volume 4, Number 5, - 2007 , ISSN 1449-1907

Download:
Full Text Original
Abstract : pdf doc
Home | Peta Situs | Admissions | Student Research | E-Journal
Universitas Muhammadiyah Malang © 2011
Developed by Infokom UMM
Last Update : 13 December 2016 20:46Kumpulan file jurnal