Animal Science Papers and Reports
A/C polymorphism in the â-4 defensin gene and its association with phenotypic and breeding values of milk production traits in Polish-Friesian cows*
Emilia Bagnicka**, Nina Strza³kowska, Tomasz Szreder, Beata Prusak, Artur Jَںwik, Ewa Koœciuczuk, Jَzef Krzy؟ewski, Lech Zwierzchowski
Polish Academy of Sciences Institute of Genetics and Animal Breeding
Jastrz.biec, 05.552 Wolka Kosowska, Poland.
Two novel single nucleotide polymorphisms (SNPs) were found in the bovine â4-defensin gene
intron – A/C transversion at position 1674 and C/T transition at position 1877 – both recognized
with BsrI endonuclease. Observed frequencies of the A1674C AA, AC, CC genotypes were 0.65, 0.32 and 0.03, respectively, while those of alleles A and C – 0.81 and 0.19. For the C1877T polymorphism in the Polish-Friesian (PF) population studied only the CC homozygotes (frequency 0.94) and CT heterozygotes (frequency 0.06) were found. Associations were evaluated between the A1687C polymorphism and milk production traits of cows. The data set comprised 8814 records of daily milk, fat, protein and ECM yields, fat, protein, lactose and dry matter contents, and somatic cell count (SCC) of milk of 352 cows. Moreover, 897 records were used of milk fat and milk protein yield and content achiewed in the whole and the standard 305-day lactation, as well as estimates of breeding values of these traits in 352 animals from official recording of milk performance (National Breeding Programme). In the whole lactation the â4-defensin gene A1674C polymorphism was found significantly related to protein yield while in the standard lactation to fat and protein contents. Moreover, the polymorphism was found related to the breeding value for protein yield, and for fat and protein content.
breeding value / â4-defensin / cattle / gene polymorphism / lactation / milk production traits
Date Deposited : 08 Aug 2011 10:43
Last Modified : 08 Aug 2011 10:43
Official URL: http://www.ighz.edu.pl/
Volume 26, Number 4, - 2008