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Animal Science Papers and Reports

.: Home > Animal Science Papers and Reports > 2005 > Volume 23 Number 3 > Tadeusz Malewski1, Stanis³aw Kamiٌski2, Lech Zwierzchowski1

Gene expression profiling of mouse mammary gland: transition from pregnancy to lactation

Tadeusz Malewski1, Stanis³aw Kamiٌski2, Lech Zwierzchowski1
1 Polish Academy of Sciences Institute of Genetics and Animal Breeding, Jastrzêbiec, 05-552 Wَlka Kosowska, Poland 2 Department of Animal Genetics, University of Warmia and Mazury in Olsztyn, Oczapowskiego 5, 10-718 Olsztyn, Poland
Abstract :

Gene expression analysis comparing pregnant and lactating mouse mammary gland was performed with Mouse Panorama Apoptosis cDNA macroarray containing 243 genes. Transition from pregnancy to lactation led to repression of 15 and induction of 24 genes, while 12 genes were found to change their expression more then twice. Expression of 16 genes was shown, not described so far in the mammary gland of mouse. Simultaneous analysis of 243 genes made it possible to begin arranging them into the gene regulation network of the mammary gland.

Keywords :
mouse / mammary gland / gene expression / cDNA macroarray

Date Deposited : 09 Aug 2011 11:35

Last Modified : 09 Aug 2011 11:35

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Volume 23, Number 3, - 2005

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