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.: Home > Animal Science Papers and Reports > 2004 > Volume 22 Number 3 > Andrzej Maj, Ma³gorzata Korczak, Jolanta Oprz¹dek, Lech Zwierzchowski, Edward Dymnicki

TG-repeat length polymorphism in the 5’-noncoding region of the growth hormone receptor gene in cattle and its association with meat production traits

Andrzej Maj, Ma³gorzata Korczak, Jolanta Oprz¹dek, Lech Zwierzchowski, Edward Dymnicki
Polish Academy of Sciences Institute of Genetics and Animal Breeding, Jastrzêbiec, 05-552 Wَlka Kosowska, Poland
Abstract :

A variable TG-repeat polymorphism was studied in the bovine growth hormone receptor (GHR) gene 5پf.noncoding region. A total of seven alleles of the GHR gene were detected in six breeds. The length of the PCR-amplified variable region was from 306 to 320 bp, corresponding to 14 to 21 TG-repeats. Three additional alleles not reported so far, with 14, 19, and 21 TG-repeats were found. The associations between TG microsatellite genotypes and live body weight, daily live weight gain and carcass traits were studied in bulls of five beef breeds and Polish Black-and-White (Friesian) dairy cattle. In the latter the TG-repeat polymorphism in the 5پf-noncoding region of the bovine gene GHR was significantly associated with mean body live weight, daily live weight gain, cold carcass weight and weight of lean and fat in valuable cuts. The longest 320-bp allele, with 21 TG repeats, was superior for most carcass traits, but when the growth rate was considered, the 320-bp allele homozygotes proved inferior to others.

Keywords :
cattle / carcass / fattening / gene / GHR / polymorphism

Date Deposited : 11 Aug 2011 10:39

Last Modified : 11 Aug 2011 10:39

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Volume 22, Number 3, - 2004

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