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Animal Science Papers and Reports

.: Home > Animal Science Papers and Reports > 2004 > Volume 22 Number 4 > Tomasz Szreder, Lech Zwierzchowski1

RFLP-TspRI polymorphism within exon 1 of the bovine estrogen receptor-ل (ERل) gene*

Tomasz Szreder, Lech Zwierzchowski1
Polish Academy of Sciences Institute of Genetics and Animal Breeding, Jastrzêbiec, 05- 552 Wَlka Kosowska, Poland
Abstract :

Estrogens regulate cellular activity by interacting with specifying intracellular receptor proteins.
Due to the functions played in reproduction, development of the mammary gland, growth and
differentiation of cells, estrogen receptors and their genes are considered candidates for the markers of production and functional traits in farm animals, including cattle. The detection is reported of a single-strand conformation polymorphism (SNP) within the coding region of the bovine estrogen receptor ERƒ؟ gene . the Aپ¨C transversion at position 503 in exon 1 . recognizable by RFLP with TspRI restriction endonuclease. This mutation does not change the amino acid sequence of ERƒ؟ protein; both triplets . CCA and CCC . code for proline. This is the first ever report on the SNP polymorphism in the bovine ER protein-coding sequence.

Keywords :
cattle / DNA sequencing / ERل / gene polymorphism / PCR-RFLP

Date Deposited : 11 Aug 2011 13:13

Last Modified : 12 Aug 2011 10:06

Official URL: http://www.ighz.edu.pl/

Volume 22, Number 4, - 2004

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