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.: Home > Animal Science Papers and Reports > 2003 > Volume 21 Number 2 > Marek Œwitoٌski, Agata Chmurzyٌska, Mariusz Maوkowski

Searching for genes controlling fatness traits in pigs – a review*

Marek Œwitoٌski, Agata Chmurzyٌska, Mariusz Maوkowski
Department of Genetics and Animal Breeding, The August Cieszkowski Agricultural University of Poznaٌ, Wo³yٌska 33, 60-637 Poznaٌ, Poland
Abstract :

Fat content of carcass is an important multigenic trait in pig breeding. There are reports indicating
several chromosomes, e.g. 1, 2, 4, 5, 6, 7, 12, 13, 14 and 18 which possibly harbour QTLs for fatness traits. Among QTL candidate genes there are leptin (LEP) and its receptor (Lepr), both playing essential role in food intake and energy balance. Moreover, expression level and polymorphism of the adipocyte specific transcription factors, such as CREB (cAMP response element binding protein) or C/EBP (CCAAT/enhancer-binding protein) may also cause phenotypic variation of the fatness traits. Some of the candidate QTLs, as Lep, Lepr, C/EBP and additionally H-FABP (fatty acid binding protein gene) and RYR1, are localized on chromosome 6. It is foreseen that searching for polymorphisms of the chosen genes may reveal association between a genotype and phenotypic variation of selected fatness traits. However, the studies are complex and require analysis of numerous genes. Cited are 71 references.

Keywords :
fatness traits / leptin / leptin receptor / marker genome map / QTL / pig

Date Deposited : 12 Aug 2011 10:01

Last Modified : 12 Aug 2011 10:01

Official URL: http://www.ighz.edu.pl/

Volume 21, Number 2, - 2003

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