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International Journal of Poultry Science

.: Home > International Journal of Poultry Science > 2011 > Volume 10 Number 3 > D.N. Lee, S.R. Lyu, R.C. Wang, C.F. Weng and B.J. Chen

Exhibit Differential Functions of Various Antibiotic Growth Promoters in Broiler Growth, Immune Response and Gastrointestinal Physiology

D.N. Lee, S.R. Lyu, R.C. Wang, C.F. Weng and B.J. Chen
Department of Animal Science, National Ilan University, Ilan 260, Taiwan 1 Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan 2 Department of Animal Science and Technology, National Taiwan University, Taipei 106, Taiwan
Abstract :

Six-hundred forty broilers were allotted into four dietary supplementation of none, 55 ppm bacitracin, 2.5 ppm nosiheptide, or 55 ppm Oxytetracycline (OTC) in a corn-soybean meal basal diet with eight pens in each treatment to investigate the effects of added various Antibiotic Growth Promoters (AGP) in diet on growth performance, immune response and gastrointestinal physiology. Data showed that nosiheptide supplementation but not bacitracin or OTC increased feed efficiency in starter period. The nosiheptide decreased the small intestine weight, IgA-positive cells along the intestinal tract and ileal mucosal secretory IgA (sIgA) concentration but bacitracin and OTC increased the IgA-positive cells in ileum. The nosiheptide supplementation group also elevated ileal sucrase and maltase activities and reduced the Lactobacillus counts in rectal contents as compared to the other treatment groups. In conclusion, the enhanced disaccharidase activity, diminished rectal Lactobacillus counts and reduced immune activated status are possibly the important factors for the improvement of feed efficiency of broilers on dietary nosiheptide supplementation from days 0-21.

Keywords :
Antibiotic growth promoters, broiler, immune response, microflora, small intestine

Date Deposited : 17 Feb 2015 14:10

Last Modified : 17 Feb 2015 14:10

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Volume 10, Number 3, - 2011 , ISSN 1682-8356

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