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International Journal of Poultry Science

.: Home > International Journal of Poultry Science > 2014 > Volume 13 Number 6 > Ngonda Saasa, Joyce Siwila, Ethel M'kandawire and King Shimumbo Nalubamba

Antibody Response of Non-Dewormed and Dewormed Village Chickens to Sheep Red Blood Cells

Ngonda Saasa, Joyce Siwila, Ethel M'kandawire and King Shimumbo Nalubamba
Department of Disease Control, Department of Clinical Studies, 1 2 University of Zambia, School of Veterinary Medicine, P.O. Box 32379, Lusaka 10101, Zambia
Abstract :

The economic activities of rural communities rely on small scale enterprises such as raising village chickens. However, the impact of many infectious diseases has hampered the activities of these rural communities necessitating the use of vaccines to control and mitigate the negative effects of the diseases. Understanding the effect of helminths on the immune system and ultimately on the outcome of vaccinations is important. In this study, the effect of deworming on the immune response was evaluated by antibody titres to sheep red blood cells using direct hemagglutination in 41 naturally helminth-infested village chickens. We found that the immune response of both the control and dewormed groups of chickens, respectively, to sheep red blood cells were similar at primary (mean titres 726.74 and 819.58; p = 0.78) and secondary (mean titres 1822.24 and 1792.92; p = 0.95) levels. The results show that helminth infestation of clinically healthy chickens may not grossly affect the immune response of village chickens, suggesting that naturally infested chickens can be immunized without deworming.

Keywords :
Anti-sheep red blood cells (a nti-SRBC), village chicken, immunity, helminths, hemagglutination, deworming, Zambia

Date Deposited : 24 Mar 2015 09:57

Last Modified : 24 Mar 2015 09:57

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Volume 13, Number 6, - 2014 , ISSN 1682-8356

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