UMM Logo

Universitas Muhammadiyah Malang


Free Download Journals Directory


International Journal of Poultry Science

.: Home > International Journal of Poultry Science > 2014 > Volume 13 Number 6 > K.T. Ncube, P.J. Jooste, P. Soma, E.F. Dzomba and F.C. Muchadeyi

Polymorphism of the Major Histocompatibility Complex and Genetic Structure of Southern African Village Chicken Populations

K.T. Ncube, P.J. Jooste, P. Soma, E.F. Dzomba and F.C. Muchadeyi
Department of Biotechnology and Food Technology, Tshwane University of Technology, 2 Private Bag X176, Pretoria-0001, South Africa Agricultural Research Council, Animal Production Institute, Private Bag X2, Irene-0062, South Africa 3 Discipline of Genetics, School of Life Sciences, University of KwaZulu-Natal, 4 Private Bag X01, Scottsville-3209, South Africa
Abstract :

The chicken Major Histocompatibility Complex (MHC) is a cluster of 19 genes spanning 92 kb on chromosome 16 and plays an important role in immune response. It is highly polymorphic and has been used to study adaptive genetic diversity in chickens. LEI0258 micro satellite marker that is on the BF region of the MHC and was used to investigate adaptive genetic diversity and population structures of village chickens from South Africa (n = 77), Zimbabwe (n = 60) and Malawi (n = 30). These village chickens are raised under scavenging production systems that are characterized by frequent exposure to diseases pathogens as well as fluctuations in feed supplies. The number of alleles, allele frequency and heterozygosity levels were used to measure diversity within populations whilst the Wright's fixation indices were used to analyze the level of population sub-structuring. A total of 22 alleles ranging from 188-448 bp were observed. Number of alleles averaged 12 per population. Allele frequency ranged from 1.6-37.5% and HO averaged 0.5. Wright's F statistics indicated high level of within population variability and absence of population sub-structuring amongst the South African, Malawian and Zimbabwean chickens. It was therefore concluded that LEI0258 is highly polymorphic and could be a useful marker for Southern African village chicken populations.

Keywords :
Genetic polymorphism, genetic adaptation, MHC, village chickens, population structure

Date Deposited : 24 Mar 2015 09:58

Last Modified : 24 Mar 2015 09:58

Official URL: http://www.pjbs.org/ijps/ab2538.htm

Volume 13, Number 6, - 2014 , ISSN 1682-8356

Download:
Full Text Original
Abstract : pdf doc
Home | Peta Situs | Admissions | Student Research | E-Journal
Universitas Muhammadiyah Malang © 2011
Developed by Infokom UMM
Last Update : 13 December 2016 20:46Kumpulan file jurnal