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Animal Science Papers and Reports

.: Home > Animal Science Papers and Reports > 2012 > Volume 30 Number 3 > Dorota Lewczuk, Agnieszka Korwin-Kossakowska

Genetic background of osteochondrosis in the horse – a review

Dorota Lewczuk, Agnieszka Korwin-Kossakowska
Institute of Genetics and Animal Breeding Polish Academy of Sciences, Jastrzębiec, 05- 552 Magdalenka, Poland
Abstract :
Osteochondrosis
is considered to be one of the most important problems in European sport horse
breeding, as the frequency of OC(D) reaches 25% or more of investigated populations. The present
article provides an overview of the genetic background of OC(D) evaluated in different countries.
Heritability is low (0.1-0.3) and contemporary selection methods seem not to be sufficiently effective.
New approaches regarding molecular methods have been developed and are a promising tool. These
include techniques such as whole genome scan, candidate gene analysis and SNP microarrays.
Potential candidate genes were found on chromosomes 2, 4, 16, 18, 28 and 30. The most recent
results on microarray SNP analysis using 50
000 SNP chip detected new QTL regions in the horse
genome.
Keywords :
genetics / heritability / horse / osteochondrosis / QTL / SNP

Date Deposited : 01 Apr 2015 15:40

Last Modified : 01 Apr 2015 15:40

Official URL: http://www.ighz.edu.pl/?p0=5&p1=34&o=7497

Volume 30, Number 3, - 2012

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