UMM Logo

Universitas Muhammadiyah Malang


Free Download Journals Directory


Animal Science Papers and Reports

The effect of insertion/deletion polymorphisms within the promoter and intron 1 sequences of the PRNP gene on the breeding value of Holstein-Friesian bulls

Urszula Czarnik
Department of Animal Genetics, University of Warmia and Mazury in Olsztyn, 10-719 Olsztyn, Poland
Abstract :
The aim of this study was to verify the hypothesis that insertion/deletion (
indel)
polymorphisms
within the promoter and intron 1 sequences of the prion protein (PRNP) gene can affect the
breeding value of Holstein-Friesian bulls. The experimental material included 261 Holstein-Friesian
bulls born between 1997 – 2002. It was shown that the polymorphism in the intron 1 (12 bp
indel
)
sequence had a more significant effect on the analyzed traits than a polymorphism in the promoter
(23 bp
indel
) sequence. A deletion allele within intron 1 (12del) significantly increased the bulls’
breeding value for milk yield (p=0.001), protein yield (p=0.042), type and conformation (p=0.018),
udder width (p=0.003), dairy character (p=0.004),
and
decreased days open (p=0.022). A deletion
allele (23del) at the polymorphic locus of the promoter significantly decreased the bulls’ breeding
value for milk yield (p=0.001), udder width (p=0.029) and dairy character (p=0.033). Analysis of
both alleles showed that 23del-12del haplotype increased the bulls’ breeding value for udder traits:
udder (p=0.008), fore udder (p=0.043) and udder depth (p=0.041), and decreased for fat content
(p=0.047) and conformation traits - body depth (p<0.001), chest width (p=0.029) and rear leg set
- side view (p=0.029). Also positive effect of 23del-12ins haplotype for days open (p=0.003) and days
between calving and first insemination (p=0.045) was observed.
Keywords :
ssociation / breeding value / Holstein bulls / polymorphism / PRNP gene

Date Deposited : 02 Apr 2015 13:56

Last Modified : 02 Apr 2015 13:56

Official URL: http://www.ighz.edu.pl/?p0=5&p1=34

Volume 33, Number 1, - 2015

Download:
Full Text Original
Abstract : pdf doc
Home | Peta Situs | Admissions | Student Research | E-Journal
Universitas Muhammadiyah Malang © 2011
Developed by Infokom UMM
Last Update : 13 December 2016 20:46Kumpulan file jurnal