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Animal Bioresource in Japan

.: Home > Animal Bioresource in Japan > 2010 > Volume 59 Number 2 > Kazunari K. YOKOYAMA1)2)3), Takehide MURATA1), Jianzhi PAN1)4), Koji NAKADE1), Shotaro KISHIKAWA1), Hideyo UGAI1)5), Makoto KIMURA1)6), Yukari KUJIME1), Megumi HIROSE1), Satoko MASUZAKI1), Takahito YAMASAKI1), Chitose KURIHARA1), Masato OKUBO1), Yuri NAKANO1), Yuka KUSA1), Akiko YOSHIKAWA1), Kumiko INABE1), Kazuko UENO1) and Yuichi OBATA1)7)

Genetic Materials at the Gene Engineering Division, RIKEN BioResource Center

Kazunari K. YOKOYAMA1)2)3), Takehide MURATA1), Jianzhi PAN1)4), Koji NAKADE1), Shotaro KISHIKAWA1), Hideyo UGAI1)5), Makoto KIMURA1)6), Yukari KUJIME1), Megumi HIROSE1), Satoko MASUZAKI1), Takahito YAMASAKI1), Chitose KURIHARA1), Masato OKUBO1), Yuri NAKANO1), Yuka KUSA1), Akiko YOSHIKAWA1), Kumiko INABE1), Kazuko UENO1) and Yuichi OBATA1)7)
1) Gene Engineering Division, RIKEN BioResource Center 2) Center of Excellence for Environmental Medicine, Graduate Institute of Medicine, Kaohsiung Medical University 3) Department of Molecular Preventive Medicine, Graduate School of Medicine, The University of Tokyo 4) Institute of Veterinary and Animal Husbandry, Zhejiang Academy of Agriculture Sciences 5) Division of Human Gene Therapy, Department of Medicine, University of Alabama at Birmingham 6) Imamoto Cellular Dynamics Laboratory, RIKEN Advanced Science Institute 7) RIKEN BioResource Center
Abstract :

Genetic materials are one of the most important and fundamental research resources for studying biological phenomena. Scientific need for genetic materials has been increasing and will never cease. Ever since it was established as RIKEN DNA Bank in 1987, the Gene Engineering Division of RIKEN BioResource Center (BRC) has been engaged in the collection, maintenance, storage, propagation, quality control, and distribution of genetic resources developed mainly by the Japanese research community. When RIKEN BRC was inaugurated in 2001, RIKEN DNA Bank was incorporated as one of its six Divisions, the Gene Engineering Division. The Gene Engineering Division was selected as a core facility for the genetic resources of mammalian and microbe origin by the National BioResource Project (NBRP) of the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan in 2002. With support from the scientific community, the Division now holds over 3 million clones of genetic materials for distribution. The genetic resources include cloned DNAs, gene libraries (e.g., cDNA and genomic DNA cloned into phage, cosmid, BAC, phosmid, and YAC), vectors, hosts, recombinant viruses, and ordered library sets derived from animal cells, including human and mouse cells, microorganisms, and viruses. Recently genetic materials produced by a few MEXT national research projects were transferred to the Gene Engineering Division for further dissemination. The Gene Engineering Division performs rigorous quality control of reproducibility, restriction enzyme mapping and nucleotide sequences of clones to ensure the reproducibility of in vivo and in vitro experiments. Users can easily access our genetic materials through the internet and obtain the DNA resources for a minimal fee. Not only the materials, but also information of features and technology related to the materials are provided via the web site of RIKEN BRC. Training courses are also given to transfer the technology for handling viral vectors. RIKEN BRC supports scientists around the world in the use of valuable genetic materials.

Keywords :
genetic material, genome, recombinant virus, quality control

Date Deposited : 21 Jun 2011 13:35

Last Modified : 21 Jun 2011 14:18

Official URL: http://www.jstage.jst.go.jp/browse/expanim/60/1/_contents

Volume 59, Number 2, - 2010

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