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.: Home > Animal Science Papers and Reports > 2011 > Volume 29 Number 1 > Marian Rَ؟ycki**, Katarzyna Piَrkowska, Maria Oczkowicz

Expression of contractile protein-encoding genes TPM2 and TNNT3 during ontogenesis in pigs raised in Poland

Marian Rَ؟ycki**, Katarzyna Piَrkowska, Maria Oczkowicz
Department of Genetics and Animal Breeding, National Research Institute of Animal Production, Krakowska 1, 32-083 Balice, Poland
Abstract :

Troponin is a regulatory proteins complex composed of subunits TnC, TnI, and TnT encoded
by separate genes – TNNT1, TNNT2 and TNNT3. It is a component of thin filaments (along with
actin and tropomyosin), to which calcium binds to accomplish this regulation. The TPM2 gene
encodes beta-tropomyosin. An imprinted QTL for muscle mass deposition has been detected near
the TNNT3 gene and several significant linkages between TPM2 and QTLs on chromosome 1 have
been identified. However, no significant correlation was found between polymorphism in both genes
and economically important pig traits. The study aimed at analysing the level of expression of
TNNT3 and TPM2 in the developing muscle (day 60-210 of life) and determining the expression
differences among Polish Large White, Polish Landrace, Pulawska, Duroc and Pietrain pigs. Within
the mentioned period the expression level of both genes in question did not change significantly. No
developmental pattern characteristic for all breeds was revealed. In PL gilts a highly significant
correlation was found among the level of expression in both white muscles (longissimus dorsi and
semimembranosus) and the animals’ maternal origin. The above results suggest that an unknown
polymorphism, probably located in regulatory part of the gene has an effect on the level of TNNT3
expression. Expression of the TPM2 did not change during ontogenesis and was not correlated with
maternal origin. However, significant differences among gilts of different breeds were identified.

Keywords :
gene expression / muscle development / TNNT3 / TPM2 / pigs

Date Deposited : 21 Jun 2011 16:02

Last Modified : 21 Jun 2011 16:02

Official URL: http://www.ighz.edu.pl/?p0=5&p1=34

Volume 29, Number 1, - 2011

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