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.: Home > Nature and Science > 2012 > Volume 10 Number 6 > Okonko IO1, Soleye FA2, Adeniji FO3, Okerentugba PO1

HIV and TB co-infection among patients on directly observed treatment of short course in Abeokuta, Ogun State, Nigeria

Okonko IO1, Soleye FA2, Adeniji FO3, Okerentugba PO1
1Medical Microbiology Unit, Department of Microbiology, University of Port Harcourt, East-West Road, P.M.B. 5323, Choba, Port Harcourt, Rivers State, Nigeria. 2Medical Laboratory Unit, Department of Health Services, University of Agriculture, Abeokuta, Ogun State, Nigeria. 3Department of Preventive and Social Medicine, College of Health Sciences, University of Port Harcourt, East-West Road, P.M.B. 5323, Choba, Port Harcourt, Rivers State, Nigeria. mac2finney@yahoo.com; iheanyi.okonko@uniport.edu.ng; Tel.: +234 803 538 0891
Abstract :

This study aimed to determine the prevalence of HIV and TB among patients on directly observed treatment of short-course (DOTS) in Abeokuta, Nigeria. Two hundred DOTS attendees (124 males and 76 females, age range: 16 to 75 years of age) at the Department of Health Services, UNAAB were randomly recruited for this study from January 1999 to July 2010. Samples of sputum and blood were collected and processed using standard laboratory procedures. All the patients’ sera were screened for antibodies to HIV-1/2 using two rapid ELISA kits. Sputum was examined for presence of Mycobacterium tuberculosis using Ziehl-Nelson’s staining method. The results showed that of the 200 patients enrolled in the DOTS, 30 (15.0%) patients were only acid-fast bacilli positive, 3 (1.5%) were only positive for anti-HIV antibodies and none (0.0%) was positive for both HIV antibody and TB. We observed that patients ≥ 40 years had higher infection rate for TB (21.5%) and HIV antibody (3.1%). Statistically, there was no significant difference in the distribution of HIV and TB infections with respect to age (P>0.05). Males and females appeared comparable in either infection rate (P = 0.05). Students had higher infection rate for TB (16.7%) and non-student had higher rate for HIV (1.6%); these differences were not statistically significant (P > 0.05). Those in the urban area had higher infection rate for TB (17.2%) while those in the rural area had higher infection rate for HIV (1.9%). Statistically, there was no significant difference between these values with respect to residential areas. The findings of this study have further confirmed that TB and HIV infections are common in Abeokuta, an urban area of Ogun State, Nigeria.

Keywords :
DOTS centre, blood, ELISA, HIV, Mycobacterium tuberculosis, Nigeria

Date Deposited : 16 May 2016 21:06

Last Modified : 16 May 2016 21:06

Official URL: http://www.sciencepub.net/nature/

Volume 10, Number 6, - 2012 , ISSN 1545-0740

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